I have taken both. Xeljanz and Rinvoq both are fantastic and act very quickly. I lost response to Xeljanz and then had success 5 months later with Rinvoq. I think the standard of care now due to...
I take Stelera. Absolutely no issue with constipation....
No. I don’t get sick more easily in any way. In face I think I got sicker on remicade as a stand alone....
Stelera can be relatively slow. In fact many have a late reaction to it, as in 8-10 weeks....
Sorry I just read about the concerns. You should be fine to retake it. If you want to go on Stelera be aware it takes longer to be effective then Rinvoq....
Should be no reason it wouldn’t work again. I am on it currently. Didn’t know there was an issue with pregnancy and JAK inhibitors....
Yes, I am Mr. Combined Therapy. I use rinvoq and stelera. Not sure which is doing the real job. I was on xeljanz for a year and half. Put me in complete remission. Then I flared badly for 4 months....
I did 35 sessions of HBOT a year and a half ago. I went 1.5hrs at 2.5pst. Not sure if it was the medications (stelera) or the HBOT that brought me out of my flare. There is an interesting research...
so yo were in remission from Rinvoq but because of insurance you are now taking Zeposia?...
I don't think that there would be many on the trial but the results have been very good. It is really a more specialized version of Stelera. The research shows it is safe and effective....
yes, all the best luck. I am on both Stelera and Rinvoq. I have no idea which one is working or they are working in combination. I don't plan to alter anything after being in remission for over a...
Reinduction can work but she is already on it once a month. I almost got reinduced but instead added a second biologic, Rinvoq. The combination seems to be very effective for me and I have been in a...
Zeposia is fast working and effective for first time biologic users. Rinvoq and Xeljanz are also fast acting and probably used more often currently then Zeposia. I guess the question is the...
There are numerous meds left in the tool box if remicade doesn’t work for you. We are all very lucky to live today with many different mechanisms for us to reduce our inflammation via biologics. If...
Remicade, when it works is amazing. It works incredibly quick. And it is very effective in reducing inflammation. It saved my colon 6 years ago when there was a lot else out there. It lost its...
Actually, the research would show it has to be a hard chamber to be able to get the pressure to high enough level. Also the KEY in HBO is the need to do it consecutively. As in 10 times over 14 days....
I used it last year. I am not so sure it assisted me in gaining remission, rather then my new meds. However, there is some recent research that shows it can be very beneficial to assist in reducing...
Yes. I was perfect for 18 months with xeljanz and then it stopped working. You can increase the dose but it didn’t help me....
Worked well for me!! Very quick. Good luck!!...
Well Xeljanz worked well for me until it started working and now Rinvoq, which is a JAK seems to be doing the job. Same family but slightly different types of mechanisms....
Not really that "strange" of a situation. It is from the same doctor but was attained via two different opinions. It combines stelera with rinvoq. Seems to do a great job for now....
I think both are excellent options. For sure the xeljanz if it works will bring you a quicker response. However, both are very effective....
Yes I think radiological guided pain management is the best there is. That is how I do mine....
Hip, knee, shoulder. I mean they are good but you need to do the rrehab once you inject it. It takes a week or so for the real benefit. Hate to say it but with hips sometimes replacements are the...
I am a cortisone injection specialist. Not really but I have had at least 5 on different body parts including my hip. I find they are very effective. I never have had to have more then one on a body...
Actually in this study it equates to 37% in clinical remission. An excellent result....
I think if you asked most IBD specialists they would classify JAK inhibitors, which xeljanz is a “form” of biologics. I may be wrong....
Really interesting article and study. It is similar to what I experienced but with different drugs. I think two combined can open doors that one alone can not. Of course the cost for many is...
Passer, Sorry for the delay. MY doctor is Dr. Colombel at Mount Sinai. He is co director. One of the best. Very involved in up to date trials and has lots of time for his patients. I have another GI...
No drugs are stopping the underlying cause without continually taking them. This therapy sounds very interesting....
The theory is that when there is a “mechanistic failure” of one drug the other drug can open a door that allows the drug to work again. Or so the theory is. Just happy to be in remission and my...
Now that for sure is not the case. There are various drugs on the cusp on being used for UC that are currently being used for RA or psoriasis. Some are in the same class we use now but most of them...
I take Stelera once a month and upacatinib, rinvoq daily. Really a mix between my GI in Canada, Mount Sinai in New York and a fantastic Italian GI who I have consulted with during my more desperate...
I wanted to update on my success with combined biologic therapy. I had a terrible flare from February last year until July of proctitis after my xeljanz which worked so well for me stopped working. I...
Stelera combined with Rinvoq...
The phase 2b just came out 2 days ago. Really good results. You can find online the presentation. Sorry for not being able to find or know how to post the link....
There is a new drug that had a very good phase 2b result. I don’t know how to redirect on this site but it is called Abivax 464. Small molecule that is different in reducing inflammation compared to...
I would go with xeljanz. It works very well and fast. I believe it is safe. There are risks with everything of course. I don’t think Zeposia has great success with patients refractive to other...
I have been reading about it. Very positive results. My GI in NYC claims it is undoubtedly the next big small molecule drug to come out....
Be patient on Stelera. 35% respond within 6 weeks and 25% are late responders. Those numbers are for crohns but they relate to UC as well....
Great new!!! Xeljanz is an amazing drug. Works so quickly and can be so effective. My opinion is stick with the 10mg dose twice daily. Life is long. Why rush the lower dosage? Congrats again!!!...
I went from once every two months to once a month and found I had an incredibly better response. The only problem is that I started taking upadacitinib as well, so I am not entirely sure what is...
Yes those two look like real stars. The riz will take over from Stelera and the Upa according my doctor is having crazy good results without the risks of xeljanz....
The Dr I see is Dr. Colombel. Great doctor who leads the program. Very smart. Knows the meds and the current results very well. Nice man....
My GI says Stelera puts on the breaks and accelerator the same time while Skyrizi is all accelerator!...
Just saw a top GI at Mount Sinai who said he was having very good results with rinvoq and with Zeposia. In particular he said the rinvoq was extremely effective for ulcerative colitis. I have also...
I would agree with Sara14 that remicade should be looked at. Certainly, well before Humira and I would for sure do xeljanz over Zeposia....
I think I would go Stelera. Although, I had an interesting conversation with a GI from Europe who stated he is having very good results with Ozanimod. Interestingly, he said Skyrizi (riizankimab) is...
Interestingly my GI who is the one of the top docs in my area says he has one patient who is on low dose vancomycin for chronic proctitis and it is very effective but he always needs to take it....
Thanks. I am definitely regressing. In all honesty not sure I wanted those 5 weeks of remission and then a return of symptoms. I hope a Stelera dose intensification is my answer. I was doing several...