Barnsbury, I was wondering are you still doing well on Rinvoq? I just started failing xeljanz and my GI wants me on entyvio or Stelera. I did so well on Xeljanz, as in responded in days, I thought...
Yews, I have tried cortiment. I wish it worked better for me. I can feel the disease moving up my colon but considering my scope is on Tuesday I think that jumping on the devils tick tacs...
My GI wants me on a prednisone but 4 years ago when I was hospitalized it did zero for me. Even when I was on steroid IV I was totally refractive. Seems like some nasty stuff to take without me...
I am going to try to convince him of it after my scope on Tuesday rather then flipping me over to entyvio. When I took xeljanz 18 months ago I felt better after 2 days and was remission in a month. I...
Many thanks I am in Canada and have a great program. What I would love to do is try upadacitinib for a couple weeks and see if I have a quick response to it like I did Xeljanz. It is like someone...
Thanks Poopydoop. You are correct I was meaning to suggest Rinvoq. It is another Jak. Skyrizi would be similar to Stelera in its function. I would prefer Stelera to the entyvio simply because of its...
So I am on xeljanz. It worked like a charm for me. Really bad proctitis the last 6 weeks. I am totally refractive to asa-5 and steroids. The xeljanz is working as I haven’t reached my earlier pan...
I am about to flip from xeljanz to Stelera and wonder how quickly Stelera becomes effective. I hope as quick as remicade and xeljanz but from what I read not nearly as quick....
I am in the midst of failing my second and I will keep on trucking. Lots of new alternatives out there. Every year something new and novel. A whole new group of meds from the world of MS coming to...
These tacrolimus enemas are not easy to compound. It could take a week for them to be produced. Neither the steroid enemas or asa 5 are doing a thing. In fact my proctitis is getting worse by the...
Now my GI says he wants to use tacrolimus enemas to assist me with my proctitis. Has anyone heard to this before?...
Remicade just stopped being effective and inflammation arose. Yes I am on 10mg twice daily. My options are dwindling. Stelera, entiviyo or perhaps the new MS based drugs. I will stick with the...
I have been on xeljanz for almost 2 years. It worked incredibly well for me. The last month I have had small symptoms. I had a scope 2 weeks ago and showed inflammation 2cm from the rectum. Felt...
I have been literally perfect on it for 18 months and it worked within days. Suddenly I have small amounts of blood. I ramped up the dose but still lingering. Thrown in some enemas but no real help....
I was wondering if anyone has utilized a couple new drugs on the market for UC. One being Ozanimod, known as Zeposia and the other Ixekizumab, known as Taltz. One in now in the EU and the other is...
Thanks poopydoop, I used the enema yesterday and everything was better today. I think i will stick with the 10mg and the enema. It can't hurt to use. I just felt perfect on the 5mg, so a flare was...
I started rectal last night. Did you use supp or enema? The only reason I didn’t right away is that they didn’t help me in my last flair. Did you go up to 10mg Poopydoop?...
A question for Xeljanzers. I have been in remission for over a year on 5mg daily twice on xeljanz. 10 days ago symptoms such as slight bleeding and urgency has arisen. I pumped it back up to 10mg...
Just a quick update. Nausea went way after a week!! Maybe a virus not known as covid 19? Thanks for assisting everyone and thanks to the makers of Xeljanz who make me feel normal!...
Quick question. Feeling great on xeljanz. 6 days ago started to feel nauseous following eating or drinking anything but water. It happens almost immediately following eating. I have no other colitis...
Brian Bressler is the best in BC. He is out of Vancouver....
When I was flaring it was hard to run without going to the bathroom while in a run. It is almost impossible to do. In fact I moved to a treadmill for my runs during flaring. I find cycling way...
sure. please ask away....
I had a question for those using Xeljanz. Have you gained weight since using it? I am a competitive triathlete and have put on around 7lbs since using it over the last 7 months. Now it could be...
I switched to xeljanz. Had a major improvement in a week. I have never been better in the past 3 years....
Quincy, Not really sure how to do links? It was in the Globe and Mail business section today....
Just thought i would tell IBDers who are on Xeljanz and are worried about COVID-19, that I read an interesting article that Pfizer is actually intending to test Xeljanz as a treatment for COVID-19....
I was very sick 6 months ago prior to using Xeljanz. I had 6 bloody BM's a day with ridiculous urgency. I was on remi at the time. Within a week I was feeling better and now after 3 years of in and...
The best method of us Xeljanz patients to determine the risk we are at by continuing our medication may be from what other diseases that utilize the drug such as arthritis and psoriasis are finding....
I have gained weight on xeljanz but only because i started to have a completely normal transit and BM's. Never been happier to sock on a few lbs....
I have had a tremendous amount of success the last 5 months on Xeljanz. I have had no side effects whatsoever. After 3 tough years I would say i am fully in remission....
The best IBD GI in Vancouver is Brian Bressler if you can get into see him. His entire group in fact is very good....
Sorry MarkwithIBD but Xeljanz worked incredibly for me. Literally two days after I started taking it. Totally different from the remicade where I always had a minor flare. The studies regarding its...
Thanks for the interesting article. It is good to know how the drug actually works! And I must say it is working amazing well for me. Taken it for three months since remi was losing its effectiveness...
I used remicade successfully for two years but it started to wear off for me. I was never in full remission. The last 2 months I have started using Xeljanz. Big difference within 2 days and now is...
Am i missing something? Why are you not considering biologics? Infliximab, humira, simponi, entyvio or xeljanz? If you have that kind of disruption in your life why not move up the ladder?...
i am suppose to reduce mine from 10mg twice daily to the the 5mg after the end of this week, being my first month. Very hesitant to do so. The dosing on this drug, due to it being so new to the UC...
Thanks noodlesnoodle, I went to a dietician who specializes in IBD and she said the exact same thing. Funny, that when I had active inflammation I really had no gas and now I am a gassy, smelly...
Just wondering if anyone on Xeljanz has had the side effect of extensive gas. I mean I am so grateful that my symptoms of blood, mucous and frequency improved almost instantaneously from the drug by...
Hey Everystone, Wondering how long you have been on the Xeljanz? Did I work very quickly for you as well? Did you reduce to the 5? Thanks. Lorne...
Must say that after three weeks I have not felt better for over 3 years. It actually frightens me. On remi I felt good but I knew the disease was there on Xeljanz I feel like before I had the...
My GI was just concerned that if the Xeljanz didn’t work I would be entirely unprotected if I had no remi in the system. I think the plan is if the Xeljanz works to stop utilizing the remi. The...
I wonder if it could just be a coincidence but 5 days into my Xeljanz experiment and my symptoms of constant blood and mucous has dissipated. Just a trace of blood. Seems like it would too quick for...
2.5 years. It actually was doing well for me. I wouldn’t say that I was entirely in remission but damn close. Started having more urgency and blood over the last few months. Rectal meds just aren’t...
I had a flex sig today. From the anal verge to 10cm I had ulceration consistent with Mayo 3 disease. Way worse then my January flex sig where it was only 5cm Mayo 1. Hey, I knew with my symptoms the...
I currently am pretty maxed out on remi at 7mg every 6 weeks. I have tried throwing the kitchen sink at the inflammation. I do think 5 asa enemas and suppositories help but they don’t put me in...
So after being in a flare for almost 3 months I went to see another IBD specialist in Manhattan. His view is that even if i have only active inflammation in a few cms adjacent to the rectum that the...
I was wondering how your experience has been with xeljanz the last month? I am in a 4 month stubborn flare while on remicade and have engaged in every rectal remedy possible. Remicade saved my colon...
Similar to my situation but I am on remicade. I have tried every rectal remedy and zero help. I have major urgency in the morning, with small blood at times. Nothing is improving it. The real issue...
Thanks for your response folks. My question is this. My CRP is totally normal as of yesterday but I for sure have the worst rectal inflammation since I got out of my severe flair. The remicade is...