If you look at the breakdown of who mostly died among those 1 million dead Americans, it is the same demographic as people who tend to die from the flu. The draconian measures put into place were...
I am not afraid of covid and I'm not afraid of people. I never let the government or medical institutions divide me from my friends and loved ones. I think how the government has behaved has mostly...
I haven't tried them, but curcumin and qing dai are basically anti-inflammatories. They suppress the body's ability to inflame tissue as part of the immune response. They work for some but not for...
My UC is always better in the sunnier weather, when vitamin D levels are higher. But this doesn't work for people who live in sunny places year round and have UC....
Food sources of sulfur are in bioavailable form, so the body assimilates it at a faster rate. Sulfites and additives are not bioavailable, so they must be converted by bacteria (much like how soil...
I don't have a true sulfite/sulfa allergy. When I'm flaring, my gut microbiome shifts towards hydrogen sulfide producers, as it does for most of us. Those corrode the bowel wall and increase transit...
It depends on frequency and intensity. Too much exercise increases oxidation status, which leads to excess hydrogen peroxide production in the cells, which is more than likely the root cause of UC....
I sometimes get this from prednisone. It is neurological. It can go away on its own eventually. One thing that helped me was seeing an osteopath trained in craniosacral. They can adjust the fine...
It has no effect as an antioxidant, but it can mop up bacterial toxins like LPS which sometimes has a soothing effect. The problem is, it also mops up nutrition, like minerals. I have used clays to...
Just curious what this diet consisted of? Also what are your thoughts on consuming NAC (N-acetyl cysteine) which would help increase glutathione production? Would this harm someone with genetically...
Just take immodium (loperamide). GI doctors have scared us to death about taking it, like that it might cause megacolon, but it's not going to do that if you use it just one time. After you void in...
I wish the SCD worked for me, but it didn't. Neither did any of the others. The one that came the closest was the low FODMAPS diet, which focuses more on sugars and fibers that are fermentable by...
Thanks for the correction. That's what I get for writing late at night. :) I'd be interested in what you think of the rest of what I had to say....
I've taken 3mg of naltrexone daily for 4 years now, off and on. I find it has zero effect while I'm in a full flare, but once I get about 70-80% better, naltrexone pushes me over the last hump into...
It's worth noting that a lot of sugary garbage on the market is loaded with artificial chemicals, colouring agents, and things that would irritate the gut and promote dysbiosis, *in addition* to the...
DSS is a poor model for studying colitis. I wouldn't put too much stock in this. DSS-induced colitis is essentially a burn. Now imagine butyrate, which dissociates into a weak acid, passing over that...
I don't think this test would be helpful because, even if it can tell you accurately that you have low GSH, that may not be the reason for your high hydrogen peroxide. You could easily test this by...
It's hard to make suggestions from a study that was essentially experimental, so nobody is able to say if one aspect of the formulation should be dropped or something else added. Hopefully Pravda's...
R-lipoic acid is not the same thing as R-dihydrolipoic acid. As far as I know, there is no R-DHLA anywhere on the market. I wonder how Pravda obtained it for his experiments. I am also skeptical...
If you do, please let us know if it helps you!...
Great! Let us know how it goes. Liposomal GSH is a gimmick, in my opinion. It's bioavailable and does stuff to the body, but not in the way that UC patients need. If you really want to try though, it...
Stress increases metabolic oxidation in the body, which leads to excess hydrogen peroxide release into the colon wall, which is likely the root cause of UC....
Do you bloat a lot right after eating? The only time I had your issue when I was in remission was when I ate foods I was sensitive to, or when I developed SIBO. Once the SIBO was treated, it stopped...
Great post Mike!...
Based on the above post I wrote, you can come up with some immediate things to help your UC: 1) Only take reducing-antioxidants (natural vitamin C, grape seed extract, curcumin, sulforaphane, vitamin...
Immune suppression doesn't work because: a) UC patients don't have an immune problem. The immune system is just attacking gut flora that are passing through a damaged colon wall caused by excess...
You may be right, that it will take a bunch of things to achieve sustained remission. However, if hydrogen peroxide is the most immediate, extreme factor, eliminating that could save lives without...
NAC successfully treats covid and a number of other diseases, especially those that involve mucus congestion. There is a big fight over NAC right now. The pharmaceutical industry is getting out of...
Thanks for sharing, Mike. I've seen this study. H2O2 is used by the body for many things. For example, our immune cells use it to kill bacteria after they engulf them. H2O2 being used inside of the...
Hi LowLead, thanks for your contribution. Most market ALA is the racemic form (contains both S-ALA and R-ALA), and they have opposite health effects. A few products are only the R form, but it is...
I only have an anecdote. Two years ago, my aunt who had cervical cancer had abdominal radiation following a hysterectomy, and it caused a severe UC flare that took her 6 months to recover from. She...
UC generally shows very poor response to FMT. I speak from experience on that one. I partook in a clinical trial with an infectious disease specialist running it. I received 8 FMTs over 6 weeks, and...
I rarely get scopes. Every time I am scoped, the damage it does to my bowel triggers a flare instantly and predictably. Other people are different... they can be scoped regularly and it causes no...
Plain diet ASAP, reduce all stress to zero, and increase my intake of antioxidants like crazy. If things spiral to the cascade point, I hit it hard with prednisone....
Isn't the conclusion obvious though? If you take multiple kinds of immune suppression then isn't that likely to show more success against UC symptoms? I don't understand what's groundbreaking about...
Phytosomal curcumin 500mg 2x daily Butyrate in the form of Tesseract's Probutryate 300mg 2x daily Sulforaphane (any brand) 20mg 2x daily Grapeseed extract (NOT grapeFRUIT seed extract) 400mg 2x...
I suggest you head on over to this thread and read it top to bottom: https://www.healingwell.com/community/default.aspx?f=38&m=4285467 I'm a health sciences major who will be going into either med...
The reason why some people with UC are the only ones in their family is because their relatives all have at least one functioning copy of genes that reduce hydrogen peroxide. If you're unlucky enough...
Most MDs would tell you no. My personal opinion is that you should wait. That's a lot to put on your immune system at one time. The boosters have been scientifically shown to confer minimal further...
https://www.sciencedirect.com/science/article/pii/S2213231717309163 [/quote] ROS have physiological functions. They serve as cellular signals for all kinds of normal things. For example, when cells...
Immune-mediated arthritis, like rheumatoid arthritis, is more than likely caused by microbial infection in the synovial fluid of the joints. Osteoarthritis is, well, just a result of bone...
ROS cause problems everywhere, not just the colon. Disclaimer though, ROS are used as healthy signalling molecules in the body. We need ROS to live, just like we need antioxidants to live. It's all...
I did not mention grape seed OIL. I said grape seed EXTRACT. They are very, very different things. Don't get those mixed up. Also, make sure you don't confuse GRAPE seed extract with grapeFRUIT seed...
Stress releases adrenaline which speeds up the cell metabolism significantly, which increases ROS and hydrogen peroxide. Diet aggravates a compromised colonic epithelium but is not the root cause,...
You're welcome! I hope it helps you. I'm waiting with excitement for Pravda's paper!...
Cannabinoids are strong anti-oxidants that help many people who have UC by reducing some of the oxidative damage in their bodies. They also act as a novel anti-inflammatory. It could very well be...
Oral iron causes massive oxidative damage to the colon that we as UC patients usually can't tolerate. I can't tolerate the smallest bit of supplemental iron orally. I have to take all my iron through...
Everything on that list looks good, except the last one. The last one is R-ALA (the R isomer of ALA), which is not the same as R-DHLA. Trust me when I say R-DHLA does not exist on the market...
Hi passer, I did read that paper of his. According to his videos, he has a new paper coming out with a different treatment plan that has a high success rate. Mesalamine provides topical anti-oxidant...
I have never met a GI doctor or colorectal surgeon who is open to doing colon resection on UC patients. The reason is that the UC will just spread to the healthy re-attached pieces. Surgery is a...