150 mg of Prednisone every other day

My husband has just been diagnosed with FSGS and has been started on 150 mg of Prednisone every other day.  When I picked up the meds the Pharmacists commented she had never seen a dose so high being prescribed.
Anyone have comments?  Anyone currently taking dosage this high?  Stories of prednisone??
 
If you go to the ulcerative colitis message board, there are alot of people there with experience of prednisone. They are not on it for the same reason, but they will offer some help.