Byetta

Hi I have only been on Byetta for 3 days so far, and also take 1000mg of metformin. I wanted to know if there are others out there using Byetta and if they have any side effects or weight loss? I have had some nausea, not to bad. And how is your glucose levels? Thanks, Virginia
Hello,
 
My name is Jeff and I have been on Byetta now for approx 6 weeks.  I have all the normall side effects and now that I am taking the full dosage it is worse.  My numbers have been great! I have questioned if I should continue to use Byetta but my numbers have been the best since using it,  However it really kicks your butt.
 
Jeff
gwheezy41 said...
Hi I have only been on Byetta for 3 days so far, and also take 1000mg of metformin. I wanted to know if there are others out there using Byetta and if they have any side effects or weight loss? I have had some nausea, not to bad. And how is your glucose levels? Thanks, Virginia
Other than medication, what  all the other precaution are you taking to bring down your BS.? I used to take 2000mg Metformin, now i am taking only 500mg
For Type II , if you are only depending on medication you will get long term complications such as excess micro albumin and lot of side effects of metformin.
Hi Great Guru, You are correct about the metformin, I could not handle 2000mg so I went down to 1000mg and yes I have excess miroalbumin always.
gwheezy41 said...
Hi Great Guru, You are correct about the metformin, I could not handle 2000mg so I went down to 1000mg and yes I have excess miroalbumin always.
Now you sholud explore other possibilities of  bring down the dosage to 250mg. We are here to discuss this kind matter.
Hi new to the forum...I am currently using byetta...it is a little unsettling with something so new...9 days...4lb loss and a really dangerous low...but I am hanging on to find a better alternative to insulin...too much weight gain...
Bearwoman,
Welcome to the forum. Sorry to make a new friend under these circumstances but glad to meet you. I've been on Lantus insulin at bedtime since spring and have lost weight slowly and am having great blood sugars. It's easier than putting on mascara and I'm very pleased with my results. Don't be afraid of having to go on insulin if your doctor deems it necessary. Lowered blood sugars are the main consideration here and we are all trying to get there.

Read back a bit in the forum and see what others are using to lower their sugars. You might be able to try some of their ideas as well. Take care and come back often. We like sharing and are all very caring people.


~ Jeannie

"As one goes through life one learns if you don't paddle your own canoe you don't move."
-Katherine Hepburn


"Madness takes its toll.
Please have exact change."

Hi, I am new to the forum.  I just started taking Byetta four days ago.  So far, I have had very few problems.  The biggest problem I have had is a feeling of fullness and needing to belch.  This has been helped by a little diet Coke.  I also take Protonix which helps somewhat too. I don't eat as much and I tend to feel full before I finish my meal.  I have noticed some constipation though and I usually have quite the opposite problem due to IBS.  I hope this does not cause additional problems. 
Hi,
I've been on Byetta for three weeks and it has worked wonders! I have had absolutely no side effects! In the first two weeks and 2 days I lost 10 pounds. I also take amaryl and glucophage. I limit my carbs to 45 gms. per meal. My blood sugar levels have greatly reduced. I have absolutely no more cravings for any kind of food, and my energy levels are out the roof! I have been on the 5 mg pen and am going to the 10 mg pen today. Hopefully, my results will be even better.

Post Edited (Doris H.) : 9/13/2005 8:51:28 PM (GMT-6)

Hello,

I have been on Byetta for 5 days now and the nausea seems to have gotten worse instead of better. I use the 5mg pen in the morning and in the evening. The nausea usually comes about an hour after the shot. The results have been great, however, does the nausea eventually go away?

I have been on Byetta for 3 months and I LOVE it!

I lost a little over 30 LBS and hope to loose another 20-25 and I'll be back to normal.

I had no idea how bad I was feeling until I started the injections. I feel great, my sugars are perfect and I have a lot of energy. Quality of life is something you can't replace.

The belching went away after 6 weeks and the nausea, while it could be pretty bad at times- I learned I had  to eat less than half of my normal intake, and eat my food 30 minutes or so after the injection.

No other real issue except a little constipation which went away along with the nausea. I have been on the 10 MG pen for over 2 months and I am so grateful for this little pen.

One thing I did find disturbing was that it took 2 doctors and a lot of convincing to get them to put me on Byetta.

3 Doctors said I was a candidate, but that they don't prescribe it as they get a lot of grief from the insurance company- and none of them even knew my insurance- It was just the way things are.

I hope this isn't true- a lot of people will end up suffering needlessly.

I've been on byetta for about two months. I felt great on the 5 mcg, but sick as a dog on the 10. Hoping this will pass soon. Lost about 12 lb. so far. My blood sugar is good, could be better. It ranges from 115-140 with an occasional spike if I eat too many carbs. Hoping with weight loss, the numbers improve. Also on Metformin 1000 mg. twice a day. Playing with the times to try to better my numbers.

Antacids, Pepto bismol, pepcid all help to a degree with the nausea. The other symptoms, weakness, dizziness, all seem to be there with the nausea and disappear if I can get rid of the nausea.

Look forward to sharing experiences regarding this new drug. Its very promising. Im pleased to be off my amaryl and prandin, but I know I might end up going back on them if I have to. Just giving byetta time to do its thing. I have 50 more pounds to lose, so I'm hoping I can continue with this weight loss.
I found that I did have to cut down on the Glucophage I was taking the 500 XL twice a day- I am now on the 500 only at lunch. I take 1 precose at breakfast and dinner with Byetta.
 
I wonder too if I could handle the 10 MG as the nausea sent me to bed a few times,  but it DID pass and I am very happy with the results. I haven't felt or looked better in 6 years.
You may want to talk to your doctor about adjusting your other medications until your system gets used to Byetta.
 
By the end of the 2nd month on the 10 MG I haven't had any nausea, but I have had some cramps that I noticed only coincides when I eat a heavy carb meal, like spaghetti. I have cut the portion way down and I eat a small salad before any thing like pizza or spaghetti and that has helped a lot. But I don't eat either of those foods much.
 
 
I hope that you feel better soon and that your levels improve. Mine are perfect at this time and I am just glad I stuck it out, but I know it can be hard at times!
Good luck!
Landyhawke-thanks for the encouragement.  Just knowing that the nausea will end is such a help, believe me. 
 
I felt so great on the 5, this is so hard to take.  With the 5, I habsolutely had to take the amaryl to keep my blood sugars normal, but on the 10, I don't.  I think that without the amaryl, I will lose weight more readily (amaryl increases appetite) so I'm sticking it out.  (even though I've been pretty useless lately, my house is a mess, I'm sitting here in my robe in the middle of the day with my bottle of Pepto at my side!)
 
Love to hear back from everyone else on this thread, too.  We gunea pigs have to stick together!
Glad to help, I didn't think to read chat boards when I was going through all this. I felt horrible- I remember curling up on my bed a few times and was afraid to complain to my doctor for fear she would take me off of the Byetta.

I finally broke down and spoke to my doctor who prescribed some anti nausea pills and had me back off a little on the other medication I was taking.

I learned from trail and error to wait and eat a half hour after the injection and reduce my meals and carbs, that worked for me. I found smaller meals of lean meats and mainly vegetables helped tremendously. It is funny, I hadn't mentioned it before but the carbs did cause me some problems and I have only recently braved it through a spaghetti meal with no problems- again- a very small plate of spaghetti.
Give it a try and again- hang in there if you can- I am so glad I did!

Back on the 10 dose.  Still feeling yucky, but the nausea is manageable with antacids.  Killer headaches, too. 

Has anyone had a problem with postprandial lunch numbers?  Seems after the shots, the blood sugar is beautiful (at breakfast and dinner), but at lunch, when there is not shot, it shoots up.  Going to try a no-carb lunch.  If that doesn't work, I might have to use some fast acting insulin or pills with lunch.

Hi,

Im a relatively new Byetta user as I've been taking it now for 3 weeks at the 5 dose. NO side effects whatsoever. I'm a type 2 that maxed on oral meds and was still out of control (Avandia 4 Metformin 1000 twice a day and stil in the 200's for blood sugar).

The Byetta has my 2hr postprandial readings around 80 but my fasting levels in the morning are still 140's to 150's. STILL much better than without and maybe the 10 dose will drop my fasting levels into the normal range. I have been eating very close to the injection but my meals are salads and meat so they are pretty high protein, low carb and no side effects. I have a couple times suffered chills and dizziness associated with hypoglycemia when I really didn't eat any carbs for dinner. (Easily cured with a Hagendaz ice cream bar). My big goal is to lose the Avandia and all the nasty side effects that go with it. The weight gain, the swelling of the legs, etc.

As a parting note, I use B&D ultrafine III 31g 5mm(3/16's of an inch) needles and most of the time you really can't even feel them go in. They are very very tiny and just take all the nastiness out of injections.
Just one quick note to Bearwoman who is using LANTUS.

Yes, I used Lanuts once a day also and had great fasting numbers. The problem was the postprandial spikes (2 hrs post) could be in the 200 range and thats not good! The Byetta is a bit more of a pain in the A to use but it TOTALLY controls the spikes (at least for me) and thats what would have caused me complications in the long run.
Warren- How are your postprandials after lunch? I find that since there is no mid-day shot, those postprandials are quite high, in addition to the high fastings in the morning. I am on byetta and metformin, only. Thinking of adding back my prandin at lunch and bedtime. That also might help with the queasy feeling I get after the shot, since my glucose has so far to drop with those doses. I think the rapid drop from 160 to 90 is what's making me weak with each shot. I'm on the 10 for about three weeks now and it really didn't fix that problem.

I think the ultimate answer to this problem will be in the Byetta LAR. (long acting). But that is probably a few years away, I think. Its in clinical trials now. I with they'd put a rush on it! It will be a once a month shot, won't that be nice?
Diamond- 2hr post prandials after luch are terrible. I think its a common problem, especially if you look at the graphs for the effectiveness of Byetta over time on their website. Im a 5 dose level on the Byetta so I definately wouldn't mind using it at lunch but I'll do that if the Doc says to try it. In the meantime I've been keeping my afternoon numbers reasonable by eating something very light or not eating at all for lunch and then doing the normal dinner thingy.

Its a shame since Byetta manages the spikes so well that we can't do something about Lunchtime. Incidently, as an aside, Byetta in my case is totally reliant on my oral meds. Avandamet 4/1000 twice a day for great numbers. I forgot it yesterday morning but took my Byetta anyway. My postprandials were 297 vs 70 so in my case the orals make a difference how effective the Byetta is.