Gene Variant "Powerful Predictor" of Type 2 Diabetes

Diseases & Conditions Diabetes
1
Hi there,
            we all knew that genes play a big role in "contacting"Diabetes.Our forum readers should be the best informed is my contention.
 
            I came across this article,which i hope you will all find interesting.
 
            It explains how genome mapping has identified"the two most strongly associated TCF7L2 variants (rs12255372 and rs7903146) influence the risk of progression from impaired glucose tolerance to overt diabetes".
 
            The authors warn that this test is not recommended right now for various reasons,but MARK MY WORDS- FOR MY CHIDREN AND YOUR CHILDREN AND GRAND-CHILDREN ,THIS GENE TESTING TO PREDICT DIABETES RISK WILL BECOME COMMON-PLACE.
 
genes  
2

Hi there,

              Internet has become a trusted Search weapon and provides up to date research results PROVIDED the search is conducted properly and the results obtained have the authenticity and backing of the researchers themselves.So,publishing from "internet search"is no sin and in fact is as educative as perusing medical journals.

In America a research program called the Diabetes Prevention Program or DPP was concluded in 2001,but the genetic connection was let out only in 2006 as follows:"Researchers have confirmed that a gene variant confers susceptibility to type 2 diabetes in participants of the Diabetes Prevention Program (DPP), a large clinical trial in adults at increased risk for developing type 2 diabetes. The finding, published in the July 20, 2006, issue of the New England Journal of Medicine, follows the discovery by deCode Genetics that a variant in a gene called TCF7L2 predisposes people to type 2 diabetes"

http://www.broad.mit.edu/cgi-bin/news/display_news.cgi?id=1805

Post Edited (spooky) : 7/28/2006 6:52:48 PM (GMT-6)

3
I wonder if this research will lead to preventing diabetes in the future... or discrimination against those with the 'defective' gene?

~ Jeannie

"People are like stained glass windows: They sparkle and shine when the sun's out, but when the darkness sets in, their true beauty is revealed only if there is light within."

- Elizabeth Kubler-Ross

4
Hi there,
the intention at least is to predict those at risk.The point that comes forcefully thru' is that EXERCISE and DIET MODIFICATION can beat the odds presented by the defective gene!